Esther, the last of the historical books, contains an early example of Jewish persecution. Esther, a Jewess, is chosen as the new queen for Ahasuerus, the king of Persia. Her uncle Mordecai has incurred the enmity of Haman, the evil court favorite, and so brought the threat of death to his people. Esther, through her position, is able to avert the tragedy and save her people.

Esther 6

6:13 And Haman told Zeresh his wife and all his friends every thing that had befallen him. Then said his wise men and Zeresh his wife unto him, If Mordecai be of the seed of the Jews, before whom thou hast begun to fall, thou shalt not prevail against him, but shalt surely fall before him.