Esther, the last of the historical books, contains an early example of Jewish persecution. Esther, a Jewess, is chosen as the new queen for Ahasuerus, the king of Persia. Her uncle Mordecai has incurred the enmity of Haman, the evil court favorite, and so brought the threat of death to his people. Esther, through her position, is able to avert the tragedy and save her people.

Esther 4

4:3 And in every province, whithersoever the king's commandment and his decree came, there was great mourning among the Jews, and fasting, and weeping, and wailing; and many lay in sackcloth and ashes.